1. Kita-Sommers Profiles | Facebook
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Kitra Somers. Picture of Kitra Somers. Escorts. in Lansing. Hotel incalls & outcalls in and around Lansing. (001) 517 803 7793. Adult Services. Recently added ...
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5. Encounter: Kitra returns! - ECCIE Worldwide
Encounter: Kitra returns! User ID: - Date: First week of March Name: Kitra Somers Phone: 5176040048. Email Address: KitraSomers@gmail.com. URL (Profile or Bio ...
See AlsoA Thousand Splendid SunsEncounter: Kitra returns! Encounter Reports - Michigan
6. [PDF] Establishment of a novel human CIC-DUX4 sarcoma cell line, Kitra ...
ZielenskaG. Somers. Medicine. Human pathology. 2012. 153 Citations. Add to Library. Alert. Fusion between CIC and DUX4 up-regulates PEA3 family genes in Ewing- ...
7. Alice Bertaina MD, PhD - Stanford Profiles
... Kitra-Roussou, V., Tbakhi, A., fa*gioli, F ... Somers, K., Symons, H. J., de Tersant, M., Uber ... Kitra-Roussou, V., Yesilipek, A., Wachowiak, J., Lankester ...
Alice Bertaina MD, PhD is part of Stanford Profiles, official site for faculty, postdocs, students and staff information (Expertise, Bio, Research, Publications, and more). The site facilitates research and collaboration in academic endeavors.
8. Human DUX4 and mouse Dux interact with STAT1 and broadly inhibit ...
Apr 24, 2023 · We confirmed that the Kitra-SRS sarcoma cell line expresses a CIC-DUX4 fusion mRNA containing the terminal 98 amino acids of DUX4 as previously ...
The developmental transcription factor DUX4 interacts with STAT1 and broadly suppresses expression of IFNγ-stimulated genes.
9. [PDF] Major Discipline Reporting - NJ.gov
Dec 31, 2022 · Somers Point PD. Stockton University. Ventnor ... Correctional Police Officer Kitra Davis ... Description: On March 14, 2022, Kitra Davis was served ...
10. Establishment of a novel human CIC-DUX4 sarcoma cell line, Kitra ...
Nov 1, 2019 · & Somers, G. R. The CIC-DUX4 fusion transcript is present in a subgroup of pediatric primitive round cell sarcomas. Hum. pathol. 43, 180–189 ...
Approximately 60–70% of EWSR1-negative small blue round cell sarcomas harbour a rearrangement of CIC, most commonly CIC-DUX4. CIC-DUX4 sarcoma (CDS) is an aggressive and often fatal high-grade sarcoma appearing predominantly in children and young adults. Although cell lines and their xenograft models are essential tools for basic research and development of antitumour drugs, few cell lines currently exist for CDS. We successfully established a novel human CDS cell line designated Kitra-SRS and developed orthotopic tumour xenografts in nude mice. The CIC-DUX4 fusion gene in Kitra-SRS cells was generated by t(12;19) complex chromosomal rearrangements with an insertion of a chromosome segment including a DUX4 pseudogene component. Kitra-SRS xenografts were histologically similar to the original tumour and exhibited metastatic potential to the lungs. Kitra-SRS cells displayed autocrine activation of the insulin-like growth factor 1 (IGF-1)/IGF-1 receptor (IGF-1R) pathway. Accordingly, treatment with the IGF-1R inhibitor, linsitinib, attenuated Kitra-SRS cell growth and IGF-1-induced activation of IGF-1R/AKT signalling both in vitro and in vivo. Furthermore, upon screening 1134 FDA-approved drugs, the responses of Kitra-SRS cells to anticancer drugs appeared to reflect those of the primary tumour. Our model will be a useful modality for investigating the molecular pathology and therapy of CDS.
